Week Two
Physiology: Chapter 4
Explain the function of each of the following terms:
Neuron- basic structural unit of the nervous system- Draw and label a neuron
Dendrite
Receptor
Pre-Synaptic
Synapse/synaptic cleft
Post-synaptic
Neuron, cell body
Axon
Terminal
Terminal vesicles
Neurotransmitters
Reuptake
Metabolizing enzymes
Understanding how receptors function:
Agonist
Antagonist
CNS
Brain Stem
Cerebellum
Cerebral Cortex
RAS
Basal Ganglia
Hypothalamus
Limbic System
Hypothalamus
PNS
Somatic nervous system
Sensory information neurons-(afferent)
Motor neurons-(efferent) voluntary actions
Autonomic Nervous system (ANS)
Sympathetic
Parasympathetic
Match the terms in the left column to the short definitions in the right column:
Abstinence
Experimental use
Situational use
Misuse/ Abuse
Dependency
__________________ Obsessive or compulsive drug use
__________________ Drug use in stressful circumstances
_________________Drug use for curiosity or Peer pressure
__________________Drug use causes problems
__________________No drug use at all
Chapter 5 – How and why drugs work
Write a short definition in your own words for the following terms:
1. Threshold Dose
2. Effect/side effect
3. Safety Margin
4. Lethal Dose
5. Potency
6. Toxicity
7. Metabolize/ biotransformation
8. Half Life
9. Tolerance
10. Cross tolerance
11. Adaptive Process: Pharmacodynamic tolerance (Drug dependence)
12. Withdrawal
13. Synergistic (potentiate) Drug Interaction
14. Antagonistic Drug Interaction
15. Name 2 main symptoms of Physical Dependence
16. Name 2 main symptoms of Psychological Dependence
Method of Description Onset
Administration (what happens ) (how fast)
oral
snorting
intraveneous
smoking
17. Elimination and Metabolism:
All drugs are metabolized (broken down) by the _____________(organ of the body).
18. Most metabolites are excreted out of the body through _______________.
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